![]() ![]() The results of the lip cream preparation, the results of the organoleptic examination were declared to have a semi-solid dosage form, distinctive odor and varied colors F1 pink F2 purplish red, F3 blackish red, homogeneity test results were declared homogeneous, stability test results showed that the preparation did not change shape, color and the odor of the preparation for 14 days of storage, the results of the pH test showed that the preparation was still within the permissible pH range on the use of the skin, the test results were declared non-irritating. The tests carried out included organoleptic tests, homogeneity tests, physical tests, pH tests, irritation tests and color preference tests. The extract formulas used were 25%, 50%, and 75%. The research method includes the manufacture of ethanol extract of miana leaves (Coleus scutellarioides L.) by maceration method. The purpose of this study was to formulate miana leaf extract in lip cream preparations as a natural dye. Miana leaf (Coleus scutellarioides L.) is a plant that contains anthocyanins that can provide certain dyes. Kandungan antosianin yang tinggi pada daun miana merupakan salah satu solusi yang tepat untuk menjawab kebutuhan industri khususnya industri kosmetika karena antosianin adalah pigmen pemberi warna yang dapat dikatakan aman, tidak memiliki efek toksik dibandingkan dengan penggunaan pigmen yang diperoleh secara sintetik yang mungkin memiliki potensi bersifat toksik dan menjadi kanker (Puspita et al., 2018). Banyak penelitian yang sudah dilakukan dengan menggunakan daun miana diantaranya pengujian antioksidan dengan metode DPPH (1,1 -Diphenyl-2picrylhidrazyl) memberikan nilai IC 50 33,76 ppm, pengujian aktivitas antibakteri terhadap Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Salmonella entereditidis yang membuktikan bahwa daun miana mampu menghambat pertumbuhan bakteri tersebut, pengujian terhadap penyembuhan luka infeksi bakteri memberikan hasil bahwa luka dapat disembuhkan dengan menggunakan ekstrak etanol daun miana serta efektivitas dari daun miana dalam uji toksisitas akut pada mencit sebagai hewan percobaan menunjukkan bahwa efek pengujian ekstrak etanol daun miana tidak memberikan efek toksik pada mencit (Afifah et al., 2015 Amrillah et al., 2015 Anita et al., 2019 Rahmawati, 2008) Kandungan terbesar dari daun miana adalah antosianin dimana antosianin ini adalah pigmen alami yang terdapat dalam tumbuhan larut dalam air dan merupakan golongan flavonoid dan bersifat amfoter yaitu sifat yang memiliki kemampuan untuk bereaksi baik dalam suasana asam maupun suasana basa, pada saat suasana asam senyawa antosianin akan memberikan warna merah tua dan pada suasana basa akan berubah menjadi ungu dan biru. In this journal review, a comprehensive study focused on knowledge of plant functions as immunodulators, pharmacological activities and phytochemical studies of the jawer kotok plant Coleus scutellariodes (L).Keywords: Guides, instructions, author’s kit, conference publications. ![]() Several studies have demonstrated the pharmacological exploration of Coleus scutellariodes (L) as an infectious disease (Tuberculosis), Anti-Inflammatory (vulvovaginal candidiasis), Antipyretic, Antioxidant-Active, Anti-diabetic, Anti-histamine, Anti-anthelmic. One of the substances contained in jawer kotok leaves has efficacy as an immunodulator, namely flavonoids. Lots of substances contained in this plant such as flavonoids, saponins, tannins, alkaloids, steroids. The leaves of this plant have various uses in traditional medicine for a number of diseases. ![]() blumei possesses significant anticestodal efficacy and supports its use in traditional medicine.Coleus scutellariodes (L), commonly known as Jawer kotok plant, is a medicinal plant that has many properties, one of which is as an immunodulator and some of its pharmacological activities. The study suggests that the leaves extract of C. The standard anticestodal drug, praziquantel at 25 mg/kg single dose revealed 100% reduction in both of EPG and worm counts. ![]() The maximum efficacy of leave extract was observed with 2000 mg/kg dose reducing the EPG and worm counts by 55.46%-69.75% and 63.83% respectively. The results showed that the efficacy of leaves extract was dose dependent. The efficacy of the leave extract was determined in terms of eggs per gram of feces (EPG) and worms reduction at necropsy. microstoma infected mice for 3 consecutive days. microstoma infections in the single doses of 250, 500, 1000, and 2000 mg kg-1 body weight. The aim of the study was to evaluate the effectivity of anticestode of ethanol leaves extract againts Hymenolepis microstoma infections in mice. Previous in vitro study showed that ethanol extract had the strongest anticestode activity compared to chloroform, hexane and aquaous extracts. Coleus blumei is a herbal plant used in the traditional medicine in Indonesia to expel the intestinal worm infections. ![]()
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